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Figure 1 | Molecular Medicine

Figure 1

From: Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery

Figure 1

LPS induces mortality and tail fin edema in zebrafish larvae. (A) LPS dose-dependently induces mortality in 3 DPF zebrafish larvae (an average of 3 trials with 10 larvae per treatment). (B) The different concentrations of LPS tested show different phenotypes in these larvae (40 larvae/LPS concentration at 6 h post LPS exposure). A predominant phenotype is the LPS-induced tail fin edema and tissue damage observed in the larvae treated with 100 µg/mL LPS. (C, D) This phenotype worsens over time and results in mortality if untreated.

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