Figure 4
From: Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery
Immune cell migration in endotoxemic zebrafish. (A, B) LPS exposure in mpx: GFP larvae causes extravascular migration of neutrophils from major blood vessels, namely the dorsal aorta (n = 7/treatment). (C, D) LPS exposure in coro1a:eGFP;lyz:Dsred also induces migration of macrophages out of the intravascular space into extravascular fluid in edematous tails (n = 7/treatment). DA: dorsal aorta