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Figure 1 | Molecular Medicine

Figure 1

From: Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates With Progression of Human Myeloma

Figure 1

ADO levels in BM plasma obtained from asymptomatic MGUS/SMM and symptomatic MM patients. BM plasma samples were analyzed by HPLC. (A) HPLC profile of a representative MM patient (X.I. = 210.84 µM). (B) ADO confirmed by specific standard spiking (50 µmol/L) in the BM aspirate from a MM patient (X.I). (C–D) Representative ADO HPLC profiles from one patient with MGUS (C) and one with SMM (D).

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Molecular Medicine

ISSN: 1528-3658