Figure 3
From: Dabigatran Potentiates Gemcitabine-Induced Growth Inhibition of Pancreatic Cancer in Mice
Effect of dabigatran in combination with gemcitabine on pancreatic cancer growth and tumor cell dissemination. (A) Pancreatic tumors derived 5 wks after tumor cell inoculation from gemcitabine- and dabigatran/gemcitabine-treated mice. (B) Weight and size of tumors depicted in (A). Indicated is the mean ± SEM (n = 8 mice per group). ***P < .0001. (C) Number of mice with distant metastasis in the indicated organs at the time of euthanization (8 mice per group).