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Figure 3 | Molecular Medicine

Figure 3

From: A New Gene Expression Signature for Triple-Negative Breast Cancer using Frozen Fresh Tissue before Neoadjuvant chemotherapy

Figure 3

TNBC signature. (A) The heat map shows 49 differentially expressed probes (corresponding to 40 genes) in TNBC versus nTNBC. At the bottom of the figure is a color code that shows expression intensity (Z score). Blue represents low gene expression, red high gene expression. At the top of the figure is a color code for TNBC (black) and nTNBC (red) patients. In the heat map, each column is for a patient and each row is for a single probe. The right side of the heat map shows official symbol gene and probe identification. (B) Venn diagram of TNBC signature and TCGA validation. Blue circle represents 40 genes of our TNBC signature. Red circle represents 87 genes from TCGA data. Overlap of both circles (blue and red) represents nine genes that are present in both sample data using same analysis.

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