Table 1 Anthropometric and analytical characteristics of the wide body mass index cohort.

N

33

15

Age (years)

52.1 ± 10.6

52.7 ± 13.1

0.8

BMI (kg/m²)

26.6 ± 2.4

32.7 ± 2.1

<0.0001

Waist circumference (cm)

89.5 ± 6.5

106.1 ± 7.1

<0.0001

Systolic blood pressure (mmHg)

124.4 ± 13.1

140.9 ± 10.6

<0.0001

Diastolic blood pressure (mmHg)

81.3 ± 8.5

89.2 ± 12.5

0.01

Total cholesterol (mg/dL)

212.3 ± 40.1

215.1 ± 36.4

0.8

HDL cholesterol (mg/dL)

56.5 ± 12.6

53.1 ± 9.5

0.3

LDL cholesterol (mg/dL)

135.8 ± 33.3

2 ± 34.9

0.9

Fasting triglycerides (mg/dL)

78 (54.5–114)

91.5 (79–157)

0.04

Glucose 0 min post-OGTT (mg/dL)

96.2 ± 10.5

102.9 ± 11.4

0.06

Glucose 30 min post-OGTT (mg/dL)

171.5 ± 32.5

184.4 ± 30.3

0.2

HbA1c (%)

4.8 ± 0.3

5.0 ± 0.4

0.2

Fasting insulin (µU/mL)

8.7 ± 3.8

14.3 ± 5.9

<0.0001

Insulin secretion *

2.49 ± 0.42

2.54 ± 0.40

0.9

Insulin sensitivity†

0.55 ± 0.2

0.25 ± 0.1

<0.0001

Free IGF-1(ng/mL)

1.21 (0.7–2.1)

0.56 (0.3–0.9)

0.1

Neutrophil count (U/µL)

3522.4 ± 1175.3

3923.1 ± 1040.6

0.2

MCP-1 (pg/mL)

426.7 ± 139.6

312.6 ± 105.1

0.02

CCDC80 (ng/mL)

1.01 ± 0.48

0.92 ± 0.45

0.5