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Figure 4 | Molecular Medicine

Figure 4

From: The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition

Figure 4

HO-1 and TJ protein expression in stable Caco-2 cells. (A) q-PCR results confirmed that HO-1 was overexpressed; (B) Western blot results verified that HO-1 protein was up-regulated in HO-1-transfected Caco-2 cells; meanwhile, ZO-1, occludin and claudin-1 expression levels were increased compared with the control. (C, D) q-PCR and Western blot results from the sh-HO-1 group. HO-1 expression was significantly decreased in the sh-HO-1 group; ZO-1 and occludin were down-regulated as well. Data are presented as the mean ± SD from three independent experiments. **P < 0.01 compared with the corresponding control.

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Molecular Medicine

ISSN: 1528-3658