Figure 3
Manhattan plot of the association of iChip variants with radiographic severity in African Americans with autoantibody-positive RA. The x-axis indicates chromosome and position, the y-axis indicates association strength −log(p). The blue line illustrates suggestive statistical association (p = 1*10−4). The red line illustrates the iChip-wide level of statistical significance (p = 3.1*10−6).