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Table 2 Variants outside the HLA region associated with autoantibody-positive RA in African Americans at p < 10−4.

From: Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans

rsID Chr Position A1a OR 95% CI P value Nearest genes
rs61828386 1 172863647 G 0.69 0.58–0.82 1.79 × 10−5 TNFSF18, FASLG
rs67164098 2 68556131 A 1.67 1.31–2.13 4.65 × 10−5 CNRIP1
rs11681966 2 100759457 C 1.50 1.23–1.78 4.04 × 10−5 AFF3 b
rs10758368 9 36310778 A 0.70 0.58–0.83 5.48 × 10−5 RNF38
rs9533119 13 43049426 A 1.36 1.17–1.59 6.32 × 10−5 TNFSF11
rs2934178 15 48218221 C 0.70 0.59–0.82 2.96 × 10−5 SEMA6D
  1. Chr: chromosome.
  2. aThe test allele and minor allele for this the study.
  3. bIndicates a validated risk locus for RA.
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Molecular Medicine

ISSN: 1528-3658