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Table 3 Ninety percent credible set for pathogenic variants in trans-ethnic fine mapping of AFF3 locus in RA susceptibility.

From: Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans

rsID Chr Position Effect allele Alternate allele Z AAa Z EASb Z EURc Posterior probability
rs13003982 chr2 100759078 T C −3.80 −4.09 −5.65 0.021
rs11681966d chr2 100759457 A C −4.22 −4.09 −5.65 0.105
rs12712067 chr2 100763900 T G −3.82 −4.08 −5.69 0.029
rs4851257 chr2 100775297 T C −3.86 −4.14 −5.59 0.025
rs4851258 chr2 100780830 T C −3.68 −4.17 −5.60 0.053
rs4851261 chr2 100786717 A G −3.69 −4.17 −5.60 0.024
rs10185059 chr2 100790172 T C −3.70 −4.16 −5.63 0.027
rs10185510 chr2 100790581 T C −3.69 −4.16 −5.63 0.027
rs12712071 chr2 100793876 A G −3.61 −4.17 −5.69 0.028
rs7608424d chr2 100796543 T G −2.89 −4.15 −6.48 0.293
rs6712515d chr2 100806514 T C −2.31 −3.66 −6.91 0.119
rs9653442d chr2 100825367 T C −2.43 −3.50 −6.95 0.188
  1. Chr: chromosome.
  2. aZ-score from our study of African Americans.
  3. bZ-score for East Asians from the trans-ethnic meta-analysis of Okada et al.
  4. cZ-score for Europeans from Okada et al.
  5. dDenotes that the variant was the index variant reported in this study, or in another genome-wide association study.
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Molecular Medicine

ISSN: 1528-3658