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Table 4 Variants genotyped on the iChip associated with RA radiographic severity in African Americans. Zero and count refer to the model coefficients for the portions of the zero inflated negative binomial model.

From: Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans

rsID Chr Position A1a Statistic Effect size 95% CI P value Gene locus
rs228702 1 7945520 G IRR 0.58 0.44–0.76 6.33 × 10−5 tnfrsf9 b
rs13014054 2 33678924 A IRR 0.53 0.39–0.71 2.92 × 10−5 RASGRP3
rs73055463 2 204712807 C OR 1.99 1.38–2.86 4.72 × 10−5 CTLA4 b
rs7034499 9 123687231 C OR 2.27 1.49–3.46 9.60 × 10−5 TRAF1-C5 b
rs7077067 10 6132692 A IRR 1.48 1.22–1.78 5.16 × 10−5 IL2RA b
rs7101785 11 696437 G IRR 1.52 1.24–1.86 5.17 × 10−5 TMEM80
rs7127742 11 118521637 G IRR 0.40 0.25–0.62 5.66 × 10−5 PHLDB1/CXCR5
rs4362159 11 128305571 A IRR 0.48 0.34–0.69 6.26 × 10−5 ETS1 b
rs506746 13 101981771 A IRR 0.53 0.41–0.68 4.19 × 10−7 NALCN/ITGBL1
rs7193451 16 11050356 G IRR 1.65 1.30–2.09 7.09 × 10−5 CLEC16A
  1. Chr: chromosome; IRR: incident rate ratio.
  2. aThe allele tested in this study.
  3. bIndicates a validated risk locus for RA.