Table 4 Variants genotyped on the iChip associated with RA radiographic severity in African Americans. Zero and count refer to the model coefficients for the portions of the zero inflated negative binomial model.
rsID | Chr | Position | A1a | Statistic | Effect size | 95% CI | P value | Gene locus |
|---|---|---|---|---|---|---|---|---|
rs228702 | 1 | 7945520 | G | IRR | 0.58 | 0.44–0.76 | 6.33 × 10−5 | tnfrsf9 b |
rs13014054 | 2 | 33678924 | A | IRR | 0.53 | 0.39–0.71 | 2.92 × 10−5 | RASGRP3 |
rs73055463 | 2 | 204712807 | C | OR | 1.99 | 1.38–2.86 | 4.72 × 10−5 | CTLA4 b |
rs7034499 | 9 | 123687231 | C | OR | 2.27 | 1.49–3.46 | 9.60 × 10−5 | TRAF1-C5 b |
rs7077067 | 10 | 6132692 | A | IRR | 1.48 | 1.22–1.78 | 5.16 × 10−5 | IL2RA b |
rs7101785 | 11 | 696437 | G | IRR | 1.52 | 1.24–1.86 | 5.17 × 10−5 | TMEM80 |
rs7127742 | 11 | 118521637 | G | IRR | 0.40 | 0.25–0.62 | 5.66 × 10−5 | PHLDB1/CXCR5 |
rs4362159 | 11 | 128305571 | A | IRR | 0.48 | 0.34–0.69 | 6.26 × 10−5 | ETS1 b |
rs506746 | 13 | 101981771 | A | IRR | 0.53 | 0.41–0.68 | 4.19 × 10−7 | NALCN/ITGBL1 |
rs7193451 | 16 | 11050356 | G | IRR | 1.65 | 1.30–2.09 | 7.09 × 10−5 | CLEC16A |