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Table 1 Left ventricular pressure measurements of isolated rat hearts recorded after ischemia during the reperfusion period.

From: Nicotinic Acetylcholine Receptor-Mediated Protection of the Rat Heart Exposed to Ischemia Reperfusion

†Function, %pre-ischemia

I/R + vehicle

I/R + Galantamine

LVDP

36.8 ± 12.4

72.6 ± 17.6*

+dP/dt

20.2 ± 8.7

46.9 ± 14.7*

−dP/dt

25.7 ± 14.2

45.6 ± 11.3*

HR

48.0 ± 21.7

53.4 ± 7.8

WP

17.8 ± 11.9

38.5 ± 10.5*

  1. †Functions are LV pressures calculated as percent pre-ischemia values. Values are mean ± SD recorded at 30 min of reperfusion. LVDP, LV developed pressure; ± dP/dt, min or max developed pressure over time; HR, heart rate; WP, work product. RMANOVA was performed on data recorded between 0 and 30 min of reperfusion. Adjusted pairwise comparisons between the treatment groups show significant differences, with *p < 0.05 versus vehicle; n = 4/group.
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Molecular Medicine

ISSN: 1528-3658