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  1. Angiotensin converting enzyme inhibitor (ACEi) therapy delays the onset of renal failure in diabetic nephropathy and inhibits or delays the onset of proteinuria in several animal models.

    Authors: Emmanuel P. Peten, Liliane J. Striker, Agnes Fogo, Iekuni Ichikawa, Aneeta Patel and Gary E. Striker

    Citation: Molecular Medicine 1994 1:BF03403536

    Content type: Original Articles

    Published on:

  2. Lipopolysaccharide (LPS) is known to activate macrophages, causing the release of toxic cytokines that may provoke inflammation and shock. One of the most important and best studied of these cytokines is tumor...

    Authors: Thomas D. Geppert, Charles E. Whitehurst, Patricia Thompson and Bruce Beutler

    Citation: Molecular Medicine 1994 1:BF03403535

    Content type: Original Articles

    Published on:

  3. Thirty-six mutations that cause Gaucher disease, the most common glycolipid storage disorder, are known. Although both alleles of most patients with the disease contain one of these mutations, in a few patient...

    Authors: Ernest Beutler, Anna Demina and Terri Gelbart

    Citation: Molecular Medicine 1994 1:BF03403534

    Content type: Original Articles

    Published on:

  4. Monozygotic (MZ) twinning is a poorly understood phenomenon that may result in subtle biologic differences between twins, despite their identical inheritance. These differences may in part account for discorda...

    Authors: Velia Trejo, Catherine Derom, Robert Vlietinck, William Ollier, Alan Silman, George Ebers, Robert Derom and Peter K. Gregersen

    Citation: Molecular Medicine 1994 1:BF03403532

    Content type: Original Articles

    Published on:

  5. Reactive arthritis (ReA) is a T cell mediated inflammatory process. The immune response is primarily directed against a triggering organism, although autoimmunity has been invoked in long-lasting, antibiotic-r...

    Authors: Andreas K. H. Mertz, Angelika Daser, Mikael Skurnik, Karl-Heinz Wiesmüller, Jürgen Braun, Heiner Appel, Steven Batsford, Peihua Wu, Armin Distler and Joachim Sieper

    Citation: Molecular Medicine 1994 1:BF03403530

    Content type: Original Articles

    Published on:

  6. This investigation deals with the molecular mechanism of anti-human immunodeficiency virus type 1 (HIV-1) action of pentoxifylline (PTX) [1-(5′-oxohexyl)-3,7-dimethylxanthine] a drug widely used for the treatm...

    Authors: Debajit K. Biswas, Christoph M. Ahlers, Bruce J. Dezube and Arthur B. Pardee

    Citation: Molecular Medicine 1994 1:BF03403529

    Content type: Original Articles

    Published on:

  7. It has been proposed that the prion, the infectious agent of transmissible spongiform encephalopathies, is PrPSc, a post-translationally modified form of the normal host protein PrPC. We showed previously that mi...

    Authors: Hansruedi Büeler, Alex Raeber, Andreas Sailer, Marek Fischer, Adriano Aguzzi and Charles Weissmann

    Citation: Molecular Medicine 1994 1:BF03403528

    Content type: Original Articles

    Published on:

  8. Major symptoms and death from systemic Bacillus anthracis infections are mediated by the action of the pathogen’s lethal toxin on host macrophages. High levels of the toxin are cytolytic to macrophages, whereas l...

    Authors: Philip C. Hanna, Benjamin A. Kruskal, R. Allen B. Ezekowitz, Barry R. Bloom and R. John Collier

    Citation: Molecular Medicine 1994 1:BF03403527

    Content type: Original Articles

    Published on:

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Molecular Medicine

ISSN: 1528-3658