Immunohistochemical staining of tissue factor in human normal and cancer breast tissues
A section of normal breast tissue was stained positive (brown) in ductal epithelial cells with monoclonal anti-tissue factor antibodies (A). Adjacent sections were stained with mouse IgG as negative controls (B). (C) A normal mammary duct stained negative (blue) for tissue factor with the anti-tissue factor antibodies. An invasive ductal carcinoma section was stained with anti-tissue factor antibodies (D and E). (E) Enlarged from the area indicated by an arrow in Panel D. Anti-tissue factor antibodies stained negative in axillary lymph node metastases (F). (A, B, and C) Photographed at 500× magnification; (D) at 1250×; (E and F) at 125×.