Skip to main content

Table 1 Intron (four flanking nucleotides)/exon (amino acids) boundaries and sizes (bp) for the 15 exons of human NRAMP identified by genomic sequence analysis of YAC-derived clones.

From: Genomic Organization and Sequence of the Human NRAMP Gene: Identification and Mapping of a Promoter Region Polymorphism

Exon Number Size (bp) Intron/Exon Boundaries %AA Identity (Mouse)
EXON 1 155   Met Thr G   50
155   ATG .. 145bp .. ATG AC A G ly Asp Lys .. (43aa) … Lys Pro gtga 68
EXON 2 143 acag GT GAC AAG ………. AAA CCG Gly Thr .. (37aa) … Phe Lys gtgg 95
EXON 3 123 acag GGC ACC ………. TTC AAA Leu Leu .. (36aa) … Pro Lys gtaa 100
EXON 4 120 acag CTT CTC ………. CCt AAG Val Pro … (31aa) .. Ala Gly Ar gtgg 91
EXON 5 107 tcag GTG CCC ………. GCT GGA CG g Ile Pro .. (19aa) … Asn Tyr G gtac 100
EXON 6 71 tcag A ATC CCA ………. AAC TAC G ly Leu Arg .. (18aa) … Tyr Gin gtgg 100
EXON7 68 gtag GG CTG CGG ………. TAT GAG Tyr Val .. (48aa) … Val Lys gtag 88
EXON 8 156 gcag TAT GTG ………. GRC AAG Ser Arg .. (49aa) … Ala Ala gtag 87
EXON 9 159 gtag TCT CGA ………. GCT CGC Phe Asn .. (26aa) … Gln Gly gtga 80
EXON 10 90 gcag TTC AAC ………. CAG GGG Gly Val .. (36aa) … Met Glu gtga 98
EXON 11 120 gcag GGC GTG ………. ATG GAG Gly Phe .. (46aa) … Leu Leu gtag 94
EXON 12 150 ccag GGC TTC ………. CTG CTG Leu Pro .. (20aa) … Asn Gly Le gtga 84
EXON 13 74 ccag CTC CCG ………. AAT CCG CT u Leu Asn .. (47aa) … Tyr Leu gtga 73
EXON 14 154 ccag G CTG AAC ………. TAC CTG Val Trp .. (34aa) … Ter gtac 67
EXON 15 108 ccag GTC TGG ………. TAG   
  1. Amino acid sequence identity with murine Nramp is shown for each exon.