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Fig. 1 | Molecular Medicine

Fig. 1

From: Ciliary Neurotrophic Factor Inhibits Brain and Peripheral Tumor Necrosis Factor Production and, When Coadministered with Its Soluble Receptor, Protects Mice From Lipopolysaccharide Toxicity

Fig. 1

Effect of CNTF on LPS toxicity

Mice were treated with LPS (30 mg/kg), either with or without CNTF (10 µg/mouse) and sCNTFRα (20 µg/mouse) administered 30 min before LPS, as described in Materials and Methods. Survival was assessed daily and expressed as a percentage (data from 10 mice per group). Animals were followed for up to 7 days; further deaths did not occur over this period and surviving mice did not appear sick. *p < 0.05 versus LPS alone by Fisher’s exact test.

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Molecular Medicine

ISSN: 1528-3658