Fig. 3From: Ciliary Neurotrophic Factor Inhibits Brain and Peripheral Tumor Necrosis Factor Production and, When Coadministered with Its Soluble Receptor, Protects Mice From Lipopolysaccharide Toxicity CNTF inhibits TNF production in the brain Mice were injected i.c.v. with LPS (2.5 µg/mouse) with or without CNTF (10 µg/mouse). TNF was measured in brain homogenates 1.5 hr later, and expressed as ng/g tissue (mean ± SE, n = 5).*p < 0.01 versus LPS alone by Dunnett’s test.Back to article page