Table 1 Measured IC 50 values of a variety of peptides corresponding to regions of rat myelin basic protein (MBP), rabies glycoprotein (rabies-derived peptides [RDP]), and a peptide from αl-antitrypsin (AT) binding to I-A u
I-A u IC 50 (nM) | ||
|---|---|---|
MBP Ac 1–11 | AcASQKRPSQRHG | >100,000 |
MBP 1–11 | ASQKRPSQRHG | >100,000 |
MBP Ac 9–20 | AcRHGSKYLATAST | 20 |
MBP 11–23 | SKYLATASTMDHA | 80 |
MBP 31–47 | RHRDTGILDSLGRFFSG | >100,000 |
MBP 35–47 | TGILDSLGRFFSG | >100,000 |
MBP 42–54 | GRFFGGDRGAPKRG | 6,100 |
MBP 68–80 | YGSLPQKSHGRTQ | 5,300 |
MBP 84–106 | VVHFFKNIVTPRTPPPSQGK | >100,000 |
MBP 89–101 | VHFFKNIVTPRTP | >100,000 |
MBP 141–156 | KGVDAQGTLSKIF | 8,500 |
MBP 142–167 | KGVDAQGTLSKIFKLGGRDSRSGS | 3,800 |
MBP 152–165 | SKIFKLGGRDSRS | >100,000 |
MBP 158–170 | IFKLGGRDSRSGSP | 12,000 |
Ovalbumin 323–339 | ISQAVHAAHAEINEAGR | 25 |
al AT 148–163 | QAVHKALTIDETG | >100,000 |
RDP-1 | QVVALKPAIAAAA | 100 |
RDP-2 | AAQVVKLKEEIKVDQ | >100,000 |
RDP-3 | AAQVKSLKPEKIVDQ | 6,000 |
RDP-4 | VVSLKPEIIVDQYEY | >100,000 |