Fig. 6

Inhibition of trophozoite extract derived heme polymerization by ZnBG

Data are expressed as incorporation of radioactive heme into an insoluble polymer (hemozoin) in the presence of increasing amounts of ZnBG. The line represents the non-linear least squares fit to the data. The IC₅₀ for this particular experiment is 3.6 µM. Each data point represents mean ± standard errors of two data points from a representative experiment of n = 4.