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Table 3 P. falciparum growth in thalassemic erythrocytes as compared to age- and type-matched normal erythrocytes

From: Inhibition of Hemozoin Formation in Plasmodium falciparum Trophozoite Extracts by Heme Analogs: Possible Implication in the Resistance to Malaria Conferred by the β-Thalassemia Trait

 

Normal

Thalassemic

%

Experiment

RBC

RBC

Reduction

1

62,757

15,126

76

2

15,492

2,952

81

3

21,925

4,690

79

4

32,393

8,378

74

Average

  

77.5 ± 3.1

  1. Data are expressed as amount of radioactive hypoxanthine incorporated into actively dividing parasites, normalized to same hematocrit and parasitemia.
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Molecular Medicine

ISSN: 1528-3658