Fig. 3
From: Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury
Implantation of CSF-1-TEC and GM-CSF-TEC into the C3H strain induces renal injury in mice with the lpr mutation
Note the accumulation of cells in the renal cortex (arrows) extending from the subcapsular site in C3H-lpr mice that received CSF-1-TEC (A) and GM-CSF-TEC (B). By comparison, C3H-++ implanted with CSF-1-TEC (C) and GM-CSF-TEC (D) did not induce any notable accumulation of cells in the renal cortex. 28 days post-Ix. sc, subcapsular space. (Hematoxylin and eosin; magnification: A, 200×; B, 300×; C and D, 500×.)