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Table 6 GM-CSF-TEC implanted into MRL- lpr recipients induce a more rapid cell infiltration than CSF-1-TEC

From: Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury

TEC

Post-Ix

3 Days

7 Days

14 Days

28 Days

A. Subcapsular a

    

CSF-1

17 ° 2

27 ° 5b

32 ° 5b

29 ° 3b

GM-CSF

19 ° 3

44 ° 8b

70 ° 14b,c

68 ° 13b,c

Uninf.

12 ° 2

13 ° 1

14 ° 2

14 ° 2

B. Intrarenal a

    

CSF-1

3 ° 2

6 ° 3

15 ° 2b

14 ° 4b

GM-CSF

12 ° 4b

16 ° 4b

40 ° 6b,c

53 ° 13b,c

Uninf.

0 ° 0

0 ° 0

2 ° 1

2 ° 2

  1. aSubcapsular and intrarenal cell infiltration was evaluated by counting the numbers of cell layers in an area with the greatest lesion. Recipient were MRL-lpr mice, 10–12 weeks of age. n = 3 in each group. Number of implanted cells: 1 × 106/mouse. Uninf., retroviral uninfected TEC.
  2. bp < 0.05 versus Uninf.
  3. cp < 0.05 versus CSF-1.