Fig. 8
From: Cyclooxygenase-2-Dependent Bronchoconstriction in Perfused Rat Lungs Exposed to Endotoxin
Proposed mechanism of LPS and PAF-induced bronchoconstriction
Acetyl salicylic acid (ASA) and CGP28238 (C38) inhibit COX; dexamethasone (Dex) and actinomycin D (AcD) prevent induction of COX-2 mRNA.