Table 2 . TCR β-chain sequences of dominant CD4+ CD28− T cell clones
From: The Repertoire of CD4+ CD28− T Cells in Rheumatoid Arthritis
BV Segment | CDR3 Sequence | BJ Segment | |
|---|---|---|---|
RA patients | |||
RA-1 | BV17 | CASS TRVK NTEAFF | BJ1S1 |
RA-2 | BV14 | CASS LREG EQFF | BJ2S1 |
BV17 | CASS TSGQV TDTQYF | BJ2S3 | |
RA-3 | BV6S7 | Polyclonal | |
BV17 | CASS QDR NSPLHF | BJ1S6 | |
RA-5 | BV7 | CASS PEDSPR ETQYF | BJ2S5 |
RA-6 | BV5S1 | Polyclonal | |
BV21S3 | CASS DNGRRMA TF | BJ1S2 | |
BV22 | CASS EEN TQYF | BJ2S5 | |
RA-9 | BV18 | CASS PELAGP DTQYF | BJ2S3 |
BV18 | CASS PQRS NYGYTF | BJ1S2 | |
BV18 | CASS PGYSGSDD EQYF | BJ2S7 | |
BV22 | CASS ELWQ SGANVLTF | BJ2S6 | |
BV22 | CASS SYLHREG QFF | BJ2S1 | |
RA-10 | BV13 | CASS YPETG SYEQYF | BJ2S7 |
BV18 | CASS PELAGP ETQYF | BJ2S5 | |
Controls | |||
C-l | BV6.7 | CASS VRDER NEKLFF | BJ1S4 |
BV20 | Polyclonal | ||
C-2 | BV6.7 | CASS PHYREG DTQYF | BJ2S3 |
BV22 | CASS EASPQGAG GNTIYF | BJ1S3 | |
C-3 | BV2 | Polyclonal | |
BV13S1 | CASS QDR NTEAFF | BJ1S1 | |
C-5 | BV2 | CASS RSRLARK DTQYF | BJ2S3 |
BV2 | CASS AASRGWLTMA LFF | BJ1S4 | |
BV21S3 | CASS QLF QETQYF | BJ2S5 |