Fig. 1

Nucleotide and derived amino acid sequence of the cDNA coding for the filarial homolog of the γ -GT

Numbers on the left indicate the nucleotide number in the open reading frame. Numbers on the right indicate the amino acid residue. The numbering of the amino acids starts at the initiation codon. The predicted signal peptide, residues 1–20 (boldface), and the putative N-glycosylation sites are underlined. The thick arrow shows the presumed cleavage site for the processing of the heavy and light chain subunits. The γ-GT signature pattern motif corresponding to the sequences previously published (31) is boxed.