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Fig. 1 | Molecular Medicine

Fig. 1

From: The Transient Pore Formed by Homologous Terminal Complement Complexes Functions as a Bidirectional Route for the Transport of Autocrine and Paracrine Signals across Human Cell Membranes

Fig. 1

Uptake of 10-kD FITC-Dextran by HUVEC treated with homologous MAC

HUVEC exposed to 6 units of homologous MAC become permeable to 10-kD FITC-dextran. The whole population of HUVEC incorporated the fluorescent probe. There was no FITC-dextran incorporation either in the absence of terminal complement components, or in the presence of purified complement proteins in combinations that do not form the homologous MAC (20×).

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Molecular Medicine

ISSN: 1528-3658