Fig. 1From: The CDKN2A (p16) Gene and Human Cancer Diagrammatic representation of the involvement of (p16) in cell cycle regulation Abbreviations are as follows: CDK, cyclin-dependent kinase; PCNA, proliferating cell nuclear antigen; Rb, retinoblastoma gene product; E2F, transcription factor; P, phosphate; Tx genes, gene transcription; p16, CDKN2A gene product.Back to article page