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Table 2 Frequency of major T cell lymphoma phenotypes in transgenic mice

From: CD3-ε Overexpressed in Prothymocytes Acts as an Oncogene

Strain

% of Tumors with Phenotype

TN

CD3SP

DP

CD3+SP

26

7.1

17.9

64.3

10.7

2978

14.3

0

85.7

0

2966H

0

0

83.3

16.7

3021

0

14.3

57.1

28.6

Total

7.8

13.7

64.7

13.7

  1. Phenotypes were determined by flow cytometric analyses of the thymomal cells. In case cells from one tumor had more than one phenotype, the phenotype representing the majority of the tumor cells was chosen as the phenotype of the tumor. This table summarizes the data from flow cytometric analyses of 70 tumors. TN: CD3CD4CD8; SP: CD4+CD8 or CD4CD8+; DP: CD4+CD8+. Flow cytometric analyses also indicated that all tumors (except one) were Thy-1+CD24+, 65% were CD44+, 30% were CD25+, and 90% were CD5+.