Table 3 IFN- γ production by lamina propria T cells in the normal and diseased colon

CD Patient #1 (Ileocolonic)

Total

N

12 ± 4

<5

39 ± 8

I

39 ± 5

5

99 ± 10

αβ⁺ T cells

N

10 ± 2

10 ± 2

38 ± 10

I

46 ± 10

9 ± 3

53 ± 14

γδ⁺ T cells

(9% Vδ1 ⁺)

N

16 ± 4

7 ± 6

19 ± 2

(35% Vδ1⁺)

I

39 ± 5

12 ± 4

109 ± 5

CD Patient #2 (Ileocolonic)

Total

N

15 ± 3

8 ± 9

13 ± 2

I

61 ± 6

7 ± 7

78 ± 9

αβ⁺ T cells

N

11 ± 5

6 ± 6

23 ± 5

I

56 ± 8

13 ± 11

57 ± 8

γδ⁺ T cells

(12% Vδ1⁺)

N

17 ± 9

11 ± 8

18 ± 13

(53% Vδ1⁺)

I

38 ± 7

24 ± 10

165 ± 11

CD Patient #3 (Colonic CD)

Total

N

11 ± 6

<5

59 ± 17

I

35 ± 10

43 ± 19

78 ± 21

αβ⁺ T cells

N

29 ± 5

18 ± 9

39 ± 6

I

39 ± 7

33 ± 11

54 ± 10

γδ⁺ T cells

(15% Vδ1⁺)

N

9 ± 3

12 ± 8

35 ± 12

(43% Vδ1⁺)

I

66 ± 8

34 ± 15

177 ± 21