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Table 1 Pathological characteristics of the TG human breast tumors

From: Expression of Molecular Biomarkers in Primary Breast Tumors Implanted into a Surrogate Host: Increased Levels of Cyclins Correlate with Tumor Progression

Tissue Agea Estrogen Receptora,b Tumor Typea Gradec Lymph Noded Xenograft Growthe
144 72 Positive Focal infiltrating ductal carcinoma with extensive intraductal component G2. N +
111 74 n.d. Tubular and ductal carcinoma G3 Y +
037 76 Positive Infiltrating mammary carcinoma with features of variant lobular carcinoma G2 N +
202 84 85 Infiltrating adenocarcinoma G2/G3 N +
195 84 85 Invasive ductal carcinoma G2 Y +
432 85 Negative Residual invasive ductal carcinoma G3 N +
118 34 n.d. Invasive carcinoma G3 n.d.
003 40 10 Invasive ductal carcinoma G3 N
089 48 Negative Invasive ductal carcinoma G3 Y
062 48 n.d. Poorly differentiated infiltrating ductal carcinoma Gl Y
075 53 n.d. Infiltrating ductal carcinoma G2 Y
222 58 Negative Invasive carcinoma G2 Y
148 64 73 Invasive and ductal carcinoma G2/G3 N
198 71 72 Invasive adenocarcinoma Gl N
337 85 85 Infiltrating ductal carcinoma G3 Y
155 89 Positive Infiltrating ductal carcinoma G2 Y
  1. aThis information was obtained from surgical and pathological records from each case and was supplied anonymously by the Ohio State University Tissue Procurement Service.
  2. bEstrogen receptor values (% positive).
  3. cGrade = tubule formation, nuclear pleomorphism, mitotic scores.
  4. dLymph node = indication of metastatic malignancy in lymph node.
  5. eXenograft growth was positive (+) when a nodule at the site of the transplant was visible within 2 weeks. Growth was negative (—) when the tumor was absorbed by the host.
  6. n.d., not determined or no information available.