Molecular Medicine

Table 1 Pathological characteristics of the T_G human breast tumors

From: Expression of Molecular Biomarkers in Primary Breast Tumors Implanted into a Surrogate Host: Increased Levels of Cyclins Correlate with Tumor Progression

Tissue	Age^a	Estrogen Receptor^a,b	Tumor Type^a	Grade^c	Lymph Node^d	Xenograft Growth^e
144	72	Positive	Focal infiltrating ductal carcinoma with extensive intraductal component	G2.	N	+
111	74	n.d.	Tubular and ductal carcinoma	G3	Y	+
037	76	Positive	Infiltrating mammary carcinoma with features of variant lobular carcinoma	G2	N	+
202	84	85	Infiltrating adenocarcinoma	G2/G3	N	+
195	84	85	Invasive ductal carcinoma	G2	Y	+
432	85	Negative	Residual invasive ductal carcinoma	G3	N	+
118	34	n.d.	Invasive carcinoma	G3	n.d.	−
003	40	10	Invasive ductal carcinoma	G3	N	−
089	48	Negative	Invasive ductal carcinoma	G3	Y	−
062	48	n.d.	Poorly differentiated infiltrating ductal carcinoma	Gl	Y	−
075	53	n.d.	Infiltrating ductal carcinoma	G2	Y	−
222	58	Negative	Invasive carcinoma	G2	Y	−
148	64	73	Invasive and ductal carcinoma	G2/G3	N	−
198	71	72	Invasive adenocarcinoma	Gl	N	−
337	85	85	Infiltrating ductal carcinoma	G3	Y	−
155	89	Positive	Infiltrating ductal carcinoma	G2	Y	−

^aThis information was obtained from surgical and pathological records from each case and was supplied anonymously by the Ohio State University Tissue Procurement Service.
^bEstrogen receptor values (% positive).
^cGrade = tubule formation, nuclear pleomorphism, mitotic scores.
^dLymph node = indication of metastatic malignancy in lymph node.
^eXenograft growth was positive (+) when a nodule at the site of the transplant was visible within 2 weeks. Growth was negative (—) when the tumor was absorbed by the host.
n.d., not determined or no information available.

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ISSN: 1528-3658

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