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Fig. 2 | Molecular Medicine

Fig. 2

From: Molecular and Structural Characterization of Five Novel Mutations in the Bruton’s Tyrosine Kinase Gene from Patients with X-Linked Agammaglobulinemia

Fig. 2

Partial DNA sequence of Btk exon 2 showing mutations in P14 and P20, and heterozygosity in carriers from the family of P20

(A) normal sequence; (B) A251G in P14; (C) T250A in P20, and (D) T/A heterozygosity at position 250 in the mother/sister of P20. The sequence is read from nt 241 (bottom) to nt 259 (top). Nucleotides T250 and A251 are indicated by arrows in the normal subject (A); the corresponding alterations are marked in the patients and carriers (B–D).

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Molecular Medicine

ISSN: 1528-3658