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Table 2 Polymorphisms in the Btk gene

From: Molecular and Structural Characterization of Five Novel Mutations in the Bruton’s Tyrosine Kinase Gene from Patients with X-Linked Agammaglobulinemia

Polymorphism

Nucleotide Positiona

Exon/Intron/Domain

RFLP (+/−)b

C/T

273 (+11)

Intron 2/PH domain

TaqI (+/−)

C/T

1086

Exon 11/SH2 domain

AlwNI(−/+)

C/T

2031

Exon 18/kinase domain

AlwNI (−/+)

  1. aThe nucleotide sequence designation is from Vetrie et al. (5).
  2. b(±/±) corresponds to (C/T) at the indicated location.
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Molecular Medicine

ISSN: 1528-3658