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Fig. 6 | Molecular Medicine

Fig. 6

From: Chondroitin-4-Sulfate Impairs In Vitro and In Vivo Cytoadherence of Plasmodium falciparum Infected Erythrocytes

Fig. 6

Time-dependent dissociation of cytoadherent infected erythrocytes in presence of sera recovered from CSA-treated monkeys

Palo-Alto IRBCs selected by panning on SBEC 17 were allowed to cytoadhere on C2 cells for 2 hr. After washing, the cells were incubated 30 min (□), 1 hr (▩), or 2 hr (■) in the presence of the sera of Monkeys 0716, 1465, and 1748 collected at the indicated times after CSA injection. The cells were washed again and the remaining cytoadherent IRBCs were counted. The dissociation is expressed as the percentage of a control performed in the presence of the sera collected at time 0 (0716: 4245 ± 443; 1465: 5130 ± 1384; 1748: 5626 ± 1566 cytoadherent IRBC/mm2).

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Molecular Medicine

ISSN: 1528-3658