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Fig. 8 | Molecular Medicine

Fig. 8

From: Characterization of New Polyclonal Antibodies Specific for 40 and 42 Amino Acid-Long Amyloid β Peptides: Their Use to Examine the Cell Biology of Presenilins and the Immunohistochemistry of Sporadic Alzheimer’s Disease and Cerebral Amyloid Angiopathy Cases

Fig. 8

Immunohistochemical analysis of the temporal neocortex of a sporadic case of AD by FCA18 IgG-purified fraction

The temporal neocortex of a patient with sporadic Alzheimer’s disease was examined by immunohistochemistry using a 500-fold dilution of the IgG-purified fraction of FCA18. Immunological complexes were revealed by the biotin-streptavidin-peroxidase procedure described in Materials and Methods. White arrowheads in A, C, and D indicate mature senile plaques while black arrows (A, D) indicate diffuse plaques. Note in B (arrowhead) the labeling of a cortical arteriole. Magnification: A–C, × 100; D, × 200.

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