Fig. 9From: Characterization of New Polyclonal Antibodies Specific for 40 and 42 Amino Acid-Long Amyloid β Peptides: Their Use to Examine the Cell Biology of Presenilins and the Immunohistochemistry of Sporadic Alzheimer’s Disease and Cerebral Amyloid Angiopathy Cases Immunohistochemical analysis of the temporal neocortex of a sporadic case of AD by FCA3340 IgG-purified fraction The temporal neocortex (sporadic AD case) was incubated with a 250-fold dilution of the IgG-purified fraction of FCA3340 and immunoreactivity was revealed by the biotin-streptavidin-peroxidase method. Arrows in A label the central dense core of mature plaques without revealing diffuse lesions as also shown in B. Magnification: A, × 100; B, × 400.Back to article page