Skip to main content
Fig. 1 | Molecular Medicine

Fig. 1

From: Expression of Amphiphysin I, an Autoantigen of Paraneoplastic Neurological Syndromes, in Breast Cancer

Fig. 1

Identification of anti-amphiphysin I autoimmunity in the serum of a patient with paraneoplastic sensory neuronopathy (Patient 692). (A) Total rat brain homogenate was analyzed by Western blotting with the following sera: (a) serum of the patient, (b) serum of a normal control patient, (c) rabbit serum CD9 that recognizes amphiphysin I and II (19). (B) The epitope specificity of the autoantibodies from Patient 692 was mapped by Western blot using GST fragments corresponding to the overlapping fragments of amphiphysin I depicted. Most autoantibodies reacted with fragment V, with a weaker response to fragment III. Electrophoretic mobility of the fragments is indicated at right.

Back to article page

Molecular Medicine

ISSN: 1528-3658