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Fig. 9 | Molecular Medicine

Fig. 9

From: Expression of Amphiphysin I, an Autoantigen of Paraneoplastic Neurological Syndromes, in Breast Cancer

Fig. 9

Sequence comparison of amphiphysin I clone 3.4 from Hs578T cell line and human brain amphiphysin I. The schematic drawing illustrates the amino acid differences between the human brain isoform of amphiphysin I and the isoform encoded by clone 3.4 from a cDNA library of the Hs578T breast cancer cell line. This 42 amino acid deletion was also detectable by RT-PCR in normal human kidney, heart, and mammary tissues, as well as in at least two of the breast cancers with high-level amphiphysin I immunoreactivity in Fig. 6 above.

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