Fig. 1
From: Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice
Provocative concentrations of acetylcholine ( µ g/gm) that increased baseline airway resistance 200% (PC 200 ).
Groups of 4–18 C57BL/6 (wild-type, WT) (A), RAG-1-deficient (RAG) (B) and RAG-1- or RAG-2-deficient mice reconstituted with purified CD4+ T cells (RAG + Cells) (C) were sensitized with either saline (Saline) or Aspergillus antigens (Ag). Decreases in PC200 indicate enhanced airway hyperreactivity, with bars representing means and standard errors of the means. Significant differences (P < 0.05) between control and Ag groups are indicated (*).