Fig. 4
From: Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice
Airway hyperreactivity in B cell-deficient mice.
Groups of 4–18 C57BL/6 wild-type (WT) (A) or B cell-deficient (MuMT) mice (B) were sensitized with either saline (Saline) or Aspergillus antigens (Ag). Designated groups of MuMT mice were treated with anti-IL-5, anti-IL-4, or control (CONT Ab) monoclonal antibodies throughout the sensitization period (C). The provocative concentrations of acetylcholine (µg/gm) that increased the baseline airway resistance by 200% (PC200) are represented by bars and standard errors of the means. Significant differences (P < 0.05) between the antigen and control groups are indicated (*).