Fig. 5
From: Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice
Allergen-induced airway disease in cytokine-deficient mice.
Cohorts of 4–6 wild-type (WT), IL-4-deficient (IL-4 −/−) or IL-5-deficient (IL-5 −/−) mice were sensitized five times intranasally with either saline (Saline) or Aspergillus antigens (Ag). Four days after the last intranasal challenge, mice were anesthetized and the airway resistance quantitated as the PC200, which is represented by bars and standard errors of the means. Significant differences (p < 0.05) between the saline and Ag groups are indicated (*).