Table 1 Phenotypic characteristics of F 1 mice
Mouse Strain | No. | Genotype | Frequency | Skin Thickness (µm) | Percent of Soluble Collagen | Serum Anti-topo I Autoantibodies (µg/ml) | ||
|---|---|---|---|---|---|---|---|---|
Expected | Observed | Col I | Col V | |||||
TSK/+ | 5 | TSK/+ | 5.0 | 5 | 239 ± 6 | 12.7 ± 0.6 | 5.1 ± 1.5 | 10.3 ± 0.80 |
pN/pN | 3 | pN/pN | 3.0 | 3 | 210 ± 13 | 8.1 ± 1.7 | 2.9 ± 0.1 | 3.6 ± 0.10 |
F1 | 18 | TSK/+, pN/+ | 9.5 | 5 | 123 ± 27 | 10.3 ± 3.3 | 3.0 ± 1.4 | 4.2 ± 2.0 |
+/+, pN/+ | 9.5 | 9 | 107 ± 21 | 9.7 ± 2.9 | 2.3 ± 0.5 | 5.7 ± 3.1 | ||
ND, pN/+ | — | 4 | 97 ± 14 | 8.4 ± 3.7 | 2.8 ± 1.3 | — | ||