Skip to main content
Fig. 2 | Molecular Medicine

Fig. 2

From: Reversal of Established Rat Crescentic Glomerulonephritis by Blockade of Macrophage Migration Inhibitory Factor (MIF): Potential Role of MIF in Regulating Glucocorticoid Production

Fig. 2

Anti-MIF Ab treatment partially reverses renal histological damage in rat anti-GBM disease. The percent of glomeruli exhibiting hypercellularity (GHYP), focal and segmental lesions (FSL), and crescents (CRES) and the percent cortical interstitial lesions (TL) were scored in animals killed on day 7 of disease without any treatment (open bars), and after treatment with an irrelevant control Ab (closed bars) or an anti-MIF Ab (hatched bars) over days 7 to 21. Note that none of these glomerular or interstitial lesions are seen in normal animals. Data are shown as the mean ± SEM for six animals. *p < 0.05, **p < 0.01, ***p < 0.001, and not significant (NS), by ANOVA.

Back to article page

Molecular Medicine

ISSN: 1528-3658