Fig. 4From: High Concentration of L-Arginine Suppresses Nitric Oxide Synthase Activity and Produces Reactive Oxygen Species in NB9 Human Neuroblastoma CellsDNA damage by L-Arg. DNA damage in L-Arg-loaded NB9 was determined by estimating the formation of sub-G1 phase of DNA (1), and changes in the number of G1 (2) and G2-M (3) phases. DNA content per nucleus was evaluated in a FACScan flow cytometer after staining nuclei with propidium iodide. Left panel, 50 µM L-Arg; right panel, 2 mM L-Arg.Back to article page