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Table 1 Characteristics of female RA patients analyzed in a prospective case-control study

From: Functional Analysis of a Human Tumor Necrosis Factor α (TNF-α) Promoter Polymorphism Related to Joint Damage in Rheumatoid Arthritis

TNF Genotype TNF-238GA TNF-238GG
Cohort of 101 RA patients who had ever fulfilled the ACR criteria  
No. of patients 5 96
% Increased RF levels 75 70
% HLA-DR4+ 20 45
  Sharp Score
Study Entry (years) Mean ± SD Median Mean ± SD Median
0 13 ± 10 5 7 ± 2 0
3 35 ± 16 31 47 ± 6 29
6 45 ± 22 24 77 ± 9 52
12 76 ± 30 79 126 ± 13 111
Subgroup of 71 RA patients who suffered from definite erosive RA.   
No. of patients 4   67  
% Increased RF levels 75   82  
% HLA-DR4+ 25   51  
  Sharp Score
Study Entry (years) Mean ± SD Median Mean ± SD Median
0 5 ± 12 16 9 ± 3 0
3 44 ± 17 40 61 ± 7 42
6 57 ± 24 51 99 ± 10 90
12 94 ± 31 90 164 ± 14 165