C1 Inhibitor Gene Sequence Facilitates Frameshift Mutations

Table 1 Reversion rate and mutation type by bacterial strain ^a

Bacteria		Genotype	Reversion Rate (× 10⁻⁹)	Deletion	Insertion	Other	Total
[	RRI	F-, gyrA96	16.3 ± 7.9	7	9	14	30
[	HB101	F-, recA13, gyrA96	2.5 ± 3.7	4	21	3	28
[	JTTI	recA56	21.0 ± 27.7	22	23	5	50
[	RS2	recA56,topA10	40.8 ± 28.1	29	1	9	39

^aBracketed strains are isogenic; the top strain of the pair is the parental strain and the bottom one is the mutant. A partial genotype is included and the boldface lettering is used to accentuate difference from the parental strain. Each experiment was performed six times. The reversion rate is the average of the quotient of revertant divided by the number of viable bacteria. Standard deviation is included.

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