Fig. 2From: Alterations of p16-pRb Pathway and Chromosome Locus 9p21–22 in Sporadic Invasive Breast CarcinomasDuctal breast carcinoma with homogenous aberrant p16 expression (tumor region indicated by arrowhead). Stromal cells (fibroblasts) with normal p16 staining (arrows). Streptavidin-biotin peroxidase technique with F-12 anti-p16 antibody (see Materials and Methods) and hematoxylin counterstain (× 500).Back to article page