Fig. 3From: Alterations of p16-pRb Pathway and Chromosome Locus 9p21–22 in Sporadic Invasive Breast CarcinomasDuctal breast carcinoma with heterogenous aberrant pRb expression (the area with pRb normal expression is indicated with an arrowhead whereas the absence of pRb expression is indicated by an arrow). Streptavidin-biotin peroxidase technique with Rb1 anti-pRb antibody (see Materials and Methods) and hematoxylin counterstain (× 500).Back to article page