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Table 1 Immune parameters in 21 HIV-1-infected individuals showing positive values of reactivities to both VEINCTR-N and the full-length Fas molecule in chimeric form.

From: Immunogenicity of an Eight Amino Acid Domain Shared by Fas (CD95/Apo-I) and HIV-1 gp120. I. Structural and Antigenic Analysis

  

Peripheral Lymphocytes

Peripheral T

  
     

Cells with

Elisa Reactivities (O.D.)

 

CDC

 

CD4 +

CD8 +

Subdiploid DNA

  

Patients

Stage

Cells/µ

Cells/µl

Cells/µl

(% of PI staining)

Anti-VEINCTR-N

Anti-Fas

1) DI-B03

II

1,390

381

724

32.5 ± 4.9

0.690 ± 0.04

0.815 ± 0.03

2) DI-F12

II

981

301

567

37.5 ± 6.1

0.795 ± 0.04

0.509 ± 0.1

3) DI-F31

IV

690

122

465

43.5 ± 5.0

1.163 ± 0.15

1.384 ± 0.18

4) DI-R10

III

809

212

494

39.6 ± 11

0.985 ± 0.11

1.206 ± 0.09

5) DI-T07

II

2,907

705

1,708

21.9 ± 6.4

0.377 ± 0.03

0.705 ± 0.03

6) DI-V42

IV

550

107

308

41.5 ± 13

0.890 ± 0.07

0.511 ± 0.06

7) HY-011

II

1,415

409

892

27.5 ± 7.5

0.788 ± 0.09

1.080 ± 0.12

8) HY-106

II

1,024

328

590

30.5 ± 4.5

0.810 ± 0.09

0.957 ± 0.09

9) HY-167

II

870

309

427

28.6 ± 11.2

0.780 ± 0.05

0.952 ± 0.11

10) HY-215

III

715

225

430

N.D.

0.668 ± 0.08

0.515 ± 0.06

11) HY-227

II

918

301

560

26.5 ± 9.4

0.720 ± 0.03

1.230 ± 0.15

12) HY-304

III

706

224

503

33.0 ± 5.7

0.538 ± 0.03

1.035 ± 0.09

13) HY-417

III

780

190

515

40.8 ± 12.5

1.090 ± 0.14

1.561 ± 0.18

14) HY-432

IV

515

108

390

36.4 ± 8.5

0.765 ± 0.05

0.670 ± 0.08

15) HY-453

II

1,215

412

695

28.6 ± 5.5

0.480 ± 0.03

0.812 ± 0.09

16) HY-512

IV

640

175

406

34.3 ± 9

0.860 ± 0.1

1.015 ± 0.14

17) HY-813

III

814

290

475

N.D.

0.420 ± 0.03

0.790 ± 0.09

18) HY-903

II

1,138

220

709

38.5 ± 6.8

0.415 ± 0.02

0.563 ± 0.03

19) ID-CR21

IVc

280

9

168

N.D.

0.630 ± 0.03

0.702 ± 0.04

20) ID-CT06

IVc

594

45

386

46.3 ± 8.2

0.836 ± 0.09

1.008 ± 0.07

21) ID-CT98

IVc

389

28

306

41.5 ± 6.5

0.410 ± 0.01

0.485 ± 0.03

  1. Data include relative levels of the peripheral T cell population with subdiploid DNA content. CDC, Centers for Disease Control; PI, propidium iodide; O.D., optical density.