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Fig. 8 | Molecular Medicine

Fig. 8

From: Luteolin, an Abundant Dietary Component is a Potent Anti-leishmanial Agent that Acts by Inducing Topoisomerase II-mediated Kinetoplast DNA Cleavage Leading to Apoptosis

Fig. 8

Micrographs of Giemsa-stained splenic smears of L. donovani-infected golden hamsters after treatment with flavonoids. L. donovani-infected golden hamsters were orally administered with phosphate buffered saline (A); quercetin, 14 mg/kg body weight (B); and luteolin, 3.5 mg/kg body weight (C). Note the presence of healthy amastigotes in spleens of hamsters receiving phosphate buffered saline (A), and the patches of degraded amastigotes (arrows) in animals treated with quercetin (B) and luteolin (C). Magnification 1000X.

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