Luteolin, an Abundant Dietary Component is a Potent Anti-leishmanial Agent that Acts by Inducing Topoisomerase II-mediated Kinetoplast DNA Cleavage Leading to Apoptosis

Table 1 In vitro anti-leishmanial activity of flavonoids on intracellular amastigotes of L. donovani ^a

^aThioglycolate—elicited peritoneal macrophages of BALB/C mice were infected in vitro with L. donovani amastigotes and incubated with graded concentrations of luteolin and quercetin (dissolved in DMSO) for 2 days at 37°C for the determination of anti-leishmanial activity on intracellular amastigotes as described in “Materials and Methods.”
^bMean ± SD of triplicate determinations.

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